On MD 11, during a seemingly normal evening, Brunel collapsed. It was discovered that a combination of a mild allergic reaction and a recent vaccine protocol triggered a time bomb that was already in Brunel's body. His genetic mutations were more serious than being born mute, and his immune system is attacking his own body.

Years ago, when the Captain was still a science officer she had started a project at Daestrom that could potentially be used toward a cure for Brunel's condition. However, her research along with other similar working medical projects were all shut down and banned as part of the larger synth ban in 2385. Just how far will the crew go and to what lengths, to save Brunel's life.